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Space Physiology
Head: Prof. Dr. med. Jörn Rittweger
Virtual Institute "Portable NMR": Mobile Skin Scanners and NMR-Tomographs for Space Medicine
Development of applications for portable NMR equipment in space medicine: Within a virtual institute "Portable NMR" of the Helmholtz Assiciation we lead the subgroup "Space Medicine". Mobile NMR-instruments from materials science, using permanent magnets, are adapted for deepth selective fluid meassurenments in human skin and immaging in arms and legs.
Full article
Nutrition and bone metabolism
Research on bone metabolism and sodium regulation in metabolic balance studies; influence on macro- und micronutrients, inactivity (e.g. microgravity, bed rest) and training on human bone metabolism with special regard on distinct diseases and extreme living conditions
Full article
Integrative Muscle Physiology
Influence of long-term unloading (e.g. microgravity, bed rest), different kinds of muscle training, changes of blood flow, blood- and tissue volume and nutrition on the human skeletal-muscle; diagnosis and therapy of hereditary muscular metabolic diseases; non-invasive methods (NMR, NIRS, EMG)
Full article
Cardiovascular- and Volume Regulation
Research on interactions between neurohumoral cardiovascular regulation and water and electrolyte metabolism, especially under the influence of weightlessness and surrogate conditions (e.g. head-down tilt bed rest)
Full article
Cell and Molecular Biology (Gravitational Biology)
Influence of gravitation on cellular signal transduction pathways. All biological systems have developed under the constant influence of gravity. Thus, the question arises whether and how changed gravitational stimulation influences structure and function of organisms. Obviously, physiological changes already take place at the cellular level. Our aim is to characterize signal transduction chains, which are involved in graviperception. Model systems are human melanocytic cells. Variation of the gravitational stimulation is achieved by means of centrifuges. Also experiments with clinostats and space experiments will be performed.
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