In several studies, the European Space Agency (ESA) has commissioned an examination of the necessities and conditions for the human (long-term-) residence in space. In 1992, an extensive international study was carried out under the designation EXEMSI (Experimental Campaign for the European Manned Space Infrastructure) in the baro-chamber TITAN.
Similar to astronauts in a space station, 4 "emsinauts" lived and worked for 60 days in this closed system. They had to provide for themselves and to work on several tasks that were given to them by a team of scientists. One important aim of the investigation was the organisation of the management of the "flight".
The baro-chamber is especially well suited as a "replacement" space station because it constitutes a closed system.The station can be set to several different gas mixtures and temperatures in order to be able to create very different environmental conditions.