Led by Dr. Christa Baumstark-Khan
The Cellular Biodiagnostics group develops cellular test systems capable of examining the impact of space conditions on humans already on cellular and molecular level. Bioassays to be developed relay on the receptor-reporter principle well known for many bacterial assays. The sensing systems consist of specially designed plasmids or vectors, where promoters, which is dependent on certain environmental conditions, act as a sensing receptor. Fluorescent proteins are valuable tools for reporter components. Receptor-reporter assays allow the detection of cellular signal transduction events dependent on special environmental parameters.