The analysis of flight dynamics and structural loads is a key aspect in the design optimization for environmentally friendly and highly efficient aircraft configurations as well as for the design of their flight control systems. The institute develops automated processes and tools for multidisciplinary modelling, simulation, and efficient analysis of closed-loop controlled, flexible aircraft. Research focuses on novel analysis methods and on improved accuracy and numerical efficiency of the simulation models, in order to reliably address the complete flight domain and to guarantee short development cycles. Another focus is model- ling and analysis of challenging scenarios including complex man oeuvres and atmospheric distortions such as gusts and turbulence. Prominent examples are wake vortices and their influence on following aircraft. Our automated modelling and analysis processes for closed-loop con- trolled aircraft allow us to directly integrate them in the highly multidisciplinary optimization of the overall aircraft system.