ATV-1 was closed in the largest version of the Ariane 5 fairing on 25 February 2008 and it was placed on the top of special version of Ariane 5 two days later. The launch took place on 9 March at 04:03 CET when the Vulcain main engine was ignited and solid rocket boosters fired.
Ariane 5 twice used its upper stage engine to finetune the orbit and release ATV to the trajectory leading towards the ISS; Ariane's mission was ended 1 hours and 7 minutes after take-off when ATV separated from upper stage.